Menotti Lerro is one of the most interesting poets of modern-day Europe. Born in a small village just outside of Salerno, Southern Italy, in 1980, he has produced an impressive range of publications, including essays, poetry, fiction, autobiography, and drama. His is a poetry concerned with powerful imagery, the physicality and vulnerability of the body, the meaning of objects, the interpretation of memories, and the philosophical importance of identity. For the first time, the rich colours and textures of Lerro’s verse are available in English. This volume presents the power of the poet’s voice in all its aching magnificence and demonstrates how it represents the sounds and rhythms of a new generation.
The volume traces the founding critical theories of the autobiographical genre, from the Enlightenment period to the most recent developments, which, since the Sixties and the essays of Roy Pascal and Jean Starobinski, have had a greater and greater influence. It offers – in contrast to the essential, and by now classic, definition of Philippe Lejeune – an increased effectiveness of the poem to express the narrative purposes of autobiography, recognizing poetic writing that has the extraordinary ability to say what “the mortal language does not say,” to quote Leopardi. The works of Seamus Heaney, Thom Gunn, Carlos Barral and Jaime Gil de Biedma are analyzed here, and show an unveiling of the self through memories, places and objects that often characterize them and that allow, to whomever recalls one’s own experience through writing, the recovery and restoration of essential meanings to the reconstruction not only of subjective identity, but also of one’s own community.
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Since it was first published in 1991, The Moral Virtues and Theological Ethics has received praise from a wide range of commentators, both Catholic and Protestant. This second edition includes discussion of works that have appeared since the early 1990s, especially the first papal document to address fundamental questions of moral theology, Veritatis Splendor. Those who already have adopted the book for classroom use will welcome this new edition, while those who have just been introduced to it will find an authoritative account of the status that virtue-centered theological ethics enjoys today. Following a new preface, the text of the six chapters from the original edition remains unchanged. However, Romanus Cessario has substantially updated his notes to account for recent literature on the subject, and a new chapter that accommodates his original study to current developments in moral theology. This second edition will inspire a new generation of students and teachers.
The present selection from the Wissenschaftslehre (Sulzbach 1837) of Bernard Bolzano (1781-1848) aims at giving a compact view of his main ideas in logic, semantics, epistemology and the methodology of science. These ideas are analyzed from a modern point of view in the Introduction. Furthermore, excerpts from Bolzano's correspondence are included which yield important remarks on his own work. The translation of the sections from the Wissenschaftslehre are based on a German text, which I have located in the Manuscript Department of the University Library in Prague (signature: 75 B 459). It was one of Bolzano's own copies of his printed work and contains a vast number of corrections made by Bolzano himself, thus representing the final stage of his thought, which has gone unnoticed in previous editions. The German originals of Bolzano's letters to M. J. Fesl, J. P. Romang, R. Zimmermann and F. Pi'ihonsky are in the Literary Archive of the Pamatnfk narodnfho pfsemnictvf in Prague. The original of the letter to F. Exner belongs to the Manuscript Department of the Osterreichische Nationalbibliothek in Vienna. The original of the letter to J. E. Seidel is preserved in the Museum of the City of Ceske Budejovice.
Adolphe is a privileged and refined young man, bored by the stupidity he perceives in the world around him. After a number of meaningless conquests, he at last encounters Ellenore, a beautiful and passionate older woman. Adolphe is enraptured and gradually wears down her resistance to his declarations of love. But as they embark on an intense and tortured affair, Ellenore gives way to a flood of emotion that only serves to repel her younger lover - yet he cannot bring himself to leave her and his procrastination can only bring tragedy. Partly inspired by Constant's own stormy affair with Madame de Staël, Adolphe (1816) is a penetrating psychological depiction of love that plumbs the depths of the passions, motives and inconsistencies of the human character.
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery. Microarray Innovations: Technology and Experimentation examines the incredibly powerful nature of array technology and the ways in which it can be applied to understanding the genomic basis of disease. Explores a myriad of applications in use today This volume explores recent innovations in the microarray field and tracks the evolution of the major platforms currently used. The international panel of contributors presents a survey of the past five years’ research and advancements in microarray methods and applications and their usage in drug discovery and biomedical research. The contributions discuss improvements in automation (array fabrication and hybridization), new substrates for printing arrays, platform comparisons and contrasts, experimental design, and data normalization and mining schemes. They also review epigenomic array studies, electronic microarrays, comparative genomic hybridization, microRNA arrays, and mutational analyzes. In addition, the book provides coverage of important clinical diagnostic arrays, protein arrays, and neuroscience applications. Examines improved methodologies As microarrays have evolved steadily over time from archetypical in-house complementary DNA (cDNA) arrays to robust commercial oligonucleotide platforms, there has been a migration to higher density biochips with increasing content and better analytical methodologies. This compendium summarizes the vast advances that have been made in this technology, highlighting the supreme advantages of microarray-based approaches in the field of biomedical research. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
When Sarah leaves him-heartbroken by their inability to conceive-Pietro reverts to a younger self, leaving the dishes unwashed, his bed unmade and the post unopened. Soon afterwards, Sarah confesses that she is pregnant, but from a casual encounter. She comes to rely on Pietro's mother for support, leaving all three in a painful limbo, unable to move on or return to the way things were. Into the void falls Olmo, an old man haunted by memories of war. At first he provides a distraction, but when he asks Pietro to travel to Russia on his behalf, to right a wrong from his past, he offers this most troubled of young men the chance of a new beginning.
From its beginnings, the Church has presented itself as a human phenomenon that carries the divine within it. As a social fact, its reality given form by men and women, the Church has always affirmed that its existence surpasses the human reality of its components and that it stands as the continuation of the event of Christ's entry into human history. Why the Church?, the final volume in McGill-Queen's University Press's trilogy of Luigi Giussani's writings, explores the Church's definition of itself as both human and divine and evaluates the truth of this claim. Giussani begins by focusing on the Church as a community composed of people who are aware of themselves as defined by the gift of the Spirit, from which they derive a new conception of existence, the fruit of conversion. He then describes the Church's developing self-awareness of its dual elements of the human and divine. Concerned with verifying the Church's claim to embody Christ, Giussani situates the locus of verification in human experience, arguing that a different type of life is born in those who try to live the life of the Church. Why the Church? is a seminal study that will engage both the scholar and the general reader. Luigi Giussani is professor emeritus of the Universit Cattolica del Sacro Cuore in Milan, Italy, and is the founder of the Catholic lay movement Communion and Liberation, which is flourishing in Italy and has spread to over sixty countries throughout the world, including Canada, the United States, and Britain.
In this pithy two-part essay, Marshall Sahlins reinvigorates the debates on what constitutes kinship, building on some of the best scholarship in the field to produce an original outlook on the deepest bond humans can have. Covering thinkers from Aristotle and Lévy- Bruhl to Émile Durkheim and David Schneider, and communities from the Maori and the English to the Korowai of New Guinea, he draws on a breadth of theory and a range of ethnographic examples to form an acute definition of kinship, what he calls the “mutuality of being.” Kinfolk are persons who are parts of one another to the extent that what happens to one is felt by the other. Meaningfully and emotionally, relatives live each other’s lives and die each other’s deaths. In the second part of his essay, Sahlins shows that mutuality of being is a symbolic notion of belonging, not a biological connection by “blood.” Quite apart from relations of birth, people may become kin in ways ranging from sharing the same name or the same food to helping each other survive the perils of the high seas. In a groundbreaking argument, he demonstrates that even where kinship is reckoned from births, it is because the wider kindred or the clan ancestors are already involved in procreation, so that the notion of birth is meaningfully dependent on kinship rather than kinship on birth. By formulating this reversal, Sahlins identifies what kinship truly is: not nature, but culture.
First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.