Carina McKay is an outsider. With one parent of royal blood, she's not nobility, yet not a servant either. Critons, magical fire-breathing creatures that protect her homeland, provide the only excitement in her routine life until she meets King Marek Duncan and her destiny changes forever. To protect his heart after an arranged marriage withers to a bitter end, Marek focuses his energy on defending his lands from a rising darkness by searching for the Caller of Light, the one who summons Critons. Marek spots Carina while traveling to a distant kingdom. Despite himself, her beauty and willfulness intrigue him, and he ultimately discovers just how much he will endure to safeguard her from the lords who want to enslave her. Together, the strength of their love can overcome the obstacles keeping them apart, but only if they have the courage to follow their hearts.
Former NFL general manager and three-time Super Bowl winner Michael Lombardi reveals what makes football organizations tick at the championship level. From personnel to practice to game-day decisions that win titles, Lombardi shares what he learned working with coaching legends Bill Walsh of the 49ers, Al Davis of the Raiders, and Bill Belichick of the Patriots, among others, during his three decades in football. Why do some NFL franchises dominate year after year while others can never crack the code of success? For 30 years Michael Lombardi had a front-row seat and full access as three titans--Bill Walsh, Al Davis, and Bill Belichick--reinvented the game, turning it into a national obsession while piling up Super Bowl trophies. Now, in Gridiron Genius, Lombardi provides the blueprint that makes a successful organization click and win--and the mistakes unsuccessful organizations make that keep them on the losing side time and again. In reality, very few coaches understand the philosophies, attention to detail, and massive commitment that defined NFL juggernauts like the 49ers and the Patriots. The best organizations are not just employing players, they are building something bigger. Gridiron Genius will explain how the best leaders evaluate, acquire, and utilize personnel in ways other professional minds, football and otherwise, won't even contemplate. How do you know when to trade a player? How do you create a positive atmosphere when everyone is out to maximize his own paycheck? And why is the tight end like the knight on a chessboard? To some, game planning consists only of designing an attack for the next opponent. But Lombardi explains how the smartest leaders script everything: from an afternoon's special-teams practice to a season's playoff run to a decade-long organizational blueprint. Readers will delight in the Lombardi tour of an NFL weekend, including what really goes on during the game on and off the field and inside the headset. First stop: Belichick's Saturday night staff meeting, where he announces how the game will go the next day. Spoiler alert: He always nails it. Football dynasties are built through massive attention to detail and unwavering commitment. From how to build a team, to how to watch a game, to understanding the essential qualities of great leaders, Gridiron Genius gives football fans the knowledge to be the smartest person in the room every Sunday.
Kristin Cashore’s bestselling, award-winning fantasy Graceling tells the story of the vulnerable-yet-strong Katsa, a smart, beautiful teenager who lives in a world where selected people are given a Grace, a special talent that can be anything from dancing to swimming. Katsa’s is killing. As the king’s niece, she is forced to use her extreme skills as his thug. Along the way, Katsa must learn to decipher the true nature of her Grace… and how to put it to good use. A thrilling, action-packed fantasy adventure (and steamy romance!) that will resonate deeply with adolescents trying to find their way in the world. This ebook includes sample chapters of FIRE, BITTERBLUE, and JANE, UNLIMITED.
It had to end sometime, but Mara had no idea it would end like this. Experience the mind-blowing conclusion to the New York Times bestselling Mara Dyer trilogy. Mara Dyer wants to believe there's more to the lies she’s been told. There is. She doesn’t stop to think about where her quest for the truth might lead. She should. She never had to imagine how far she would go for vengeance. She will now. Loyalties are betrayed, guilt and innocence tangle, and fate and chance collide in this shocking conclusion to Mara Dyer’s story. Retribution has arrived.
Mara Dyer doesn’t know if she is crazy or haunted—all she knows is that everyone around her is dying in this suspenseful and “strong, inventive tale” (Kirkus Reviews). Mara Dyer doesn’t think life can get any stranger than waking up in a hospital with no memory of how she got there. It can. She believes there must be more to the accident she can’t remember that killed her friends and left her mysteriously unharmed. There is. She doesn’t believe that after everything she’s been through, she can fall in love. She’s wrong. After Mara survives the traumatizing accident at the old asylum, it makes sense that she has issues. She lost her best friend, her boyfriend, and her boyfriend’s sister, and as if that weren’t enough to cope with, her family moves to a new state in order to give her a fresh start. But that fresh start is quickly filled with hallucinations—or are they premonitions?—and then corpses, and the boundary between reality and nightmare is wavering. At school, there’s Noah, a devastatingly handsome charmer who seems determined to help Mara piece together what’s real, what’s imagined—and what’s very, very dangerous. This fast-paced psychological—or is it paranormal?—thriller will leave you breathless for its sequel, The Evolution of Mara Dyer.
In the first book of the Shaw Confessions, the companion series to the New York Times bestselling Mara Dyer novels, old skeletons are laid bare and new promises prove deadly. This is what happens after happily ever after. Everyone thinks seventeen-year-old Noah Shaw has the world on a string. They’re wrong. Mara Dyer is the only one he trusts with his secrets and his future. He shouldn’t. And both are scared that uncovering the truth about themselves will force them apart. They’re right.
The truth about Mara Dyer’s dangerous and mysterious abilities continues to unravel in the New York Times bestselling sequel to the thrilling The Unbecoming of Mara Dyer. Mara Dyer once believed she could run from her past. She can’t. She used to think her problems were all in her head. They aren’t. She couldn’t imagine that after everything she’s been through, the boy she loves would still be keeping secrets. She’s wrong. In this gripping sequel to The Unbecoming of Mara Dyer, the truth evolves and choices prove deadly. What will become of Mara Dyer next?
"Brings together leading and emerging researchers to advance understanding of the complex relationships between homelessness and health. Covering a wide range of topics from youth homelessness to end-of-life care, contributors outline policy and practice recommendations to respond to this public health crisis."--back cover.
Pulitzer Prize-winning journalist Daniel Golden exposes how academia has become the center of foreign and domestic espionage—and why that is troubling news for our nation's security. Grounded in extensive research and reporting, Spy Schools reveals how academia has emerged as a frontline in the global spy game. In a knowledge-based economy, universities are repositories of valuable information and research, where brilliant minds of all nationalities mingle freely with few questions asked. Intelligence agencies have always recruited bright undergraduates, but now, in an era when espionage increasingly requires specialized scientific or technological expertise, they’re wooing higher-level academics—not just as analysts, but also for clandestine operations. Golden uncovers unbelievable campus activity—from the CIA placing agents undercover in Harvard Kennedy School classes and staging academic conferences to persuade Iranian nuclear scientists to defect, to a Chinese graduate student at Duke University stealing research for an invisibility cloak, and a tiny liberal arts college in Marietta, Ohio, exchanging faculty with China’s most notorious spy school. He shows how relentlessly and ruthlessly this practice has permeated our culture, not just inside the US, but internationally as well. Golden, acclaimed author of The Price of Admission, blows the lid off this secret culture of espionage and its consequences at home and abroad.
Provides a global view of the recent advances in the biological sciences and the adaption of the pathogen to the host plants revealed using NGS. Molecular Omic’s is now a major driving force to learn the adaption genetics and a great challenge to the scientific community, which can be resolved through the application of the NGS technologies. The availability of complete genome sequences, the respective model species for dicot and monocot plant groups, presents a global opportunity to delineate the identification, function and the expression of the genes, to develop new tools for the identification of the new genes and pathway identification. Genome-wide research tools, resources and approaches such as data mining for structural similarities, gene expression profiling at the DNA and RNA level with rapid increase in available genome sequencing efforts, expressed sequence tags (ESTs), RNA-seq, gene expression profiling, induced deletion mutants and insertional mutants, and gene expression knock-down (gene silencing) studies with RNAi and microRNAs have become integral parts of plant molecular omic’s. Molecular diversity and mutational approaches present the first line of approach to unravel the genetic and molecular basis for several traits, QTL related to disease resistance, which includes host approaches to combat the pathogens and to understand the adaptation of the pathogen to the plant host. Using NGS technologies, understanding of adaptation genetics towards stress tolerance has been correlated to the epigenetics. Naturally occurring allelic variations, genome shuffling and variations induced by chemical or radiation mutagenesis are also being used in functional genomics to elucidate the pathway for the pathogen and stress tolerance and is widely illustrated in demonstrating the identification of the genes responsible for tolerance in plants, bacterial and fungal species.
This book is intended for practicing pathologists and cytopathologists, as well as for pathology trainees and cytotechnicians. It starts with a detailed description of the extremely important pre-analytical phase for molecular testing followed by a presentation of the key tests and their application in different organs, e.g. the lung or thyroid. Step-by-step instructions for the different assays, reporting and clinical integration of the test results are discussed. The authors help the reader to benefit from their experiences by providing a valuable tool for the implementation of these techniques in daily practice. Though the use of molecular techniques is well established in surgical biopsies, to date they are not widely used in connection with cytological material. However, in some fields like lung cancer or aspirates from the pancreas and biliary tract the only available material for diagnosis is the cytological preparation a fact that has created a need for the standardization of molecular techniques on cytology.
“The best book I’ve read in years.” —Christine Feehan The incomparable C.L. Wilson brings her phenomenal Tairen Soul novels to Avon Books! Lord of the Fading Lands is the first book in the epic romantic adventure that combines sweeping fantasy with breathtaking paranormal romance. USA Today and New York Times bestseller C. L. Wilson dazzles with a magnificent, heart-soaring tale of passion and great destiny—of the tormented Fey King Rain, the woodcutter’s daughter Ellysetta, who would be queen, and their eternal quest for true love in the mystical Fading Lands.
Cyber-terrorism and corporate espionage are increasingly common and devastating threats, making trained network security professionals more important than ever. This timely text helps you gain the knowledge and skills to protect networks using the tools and techniques of an ethical hacker. The authors begin by exploring the concept of ethical hacking and its practitioners, explaining their importance in protecting corporate and government data from cyber attacks. The text then provides an in-depth guide to performing security testing against computer networks, covering current tools and penetration testing methodologies. Updated for today’s cyber security environment, the Third Edition of this trusted text features new computer security resources, coverage of emerging vulnerabilities and innovative methods to protect networks, a new discussion of mobile security, and information on current federal and state computer crime laws, including penalties for illegal computer hacking. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.
Praise for Crime Classification Manual "The very first book by and for criminal justice professionals in the major case fields. . . . The skills, techniques, and proactive approaches offered are creatively concrete and worthy of replication across the country. . . . Heartily recommended for those working in the 'front line' of major case investigation." —John B. Rabun Jr., ACSW, Executive Vice President and Chief Operating Officer, National Center for Missing and Exploited Children "[CCM] is an outstanding resource for students pursuing forensic science degrees. It provides critical information on major crimes, which improve the user's ability to assess and evaluate." —Paul Thomas Clements, PhD, APRN-BC, CGS, DF-IAFN Drexel University Forensic Healthcare Program The landmark book standardizing the language, terminology, and classifications used throughout the criminal justice system Arranged according to the primary intent of the criminal, the Crime Classification Manual, Third Edition features the language, terms, and classifications the criminal justice system and allied fields use as they work to protect society from criminal behavior. Coauthored by a pioneer of modern profiling and featuring new coverage of wrongful convictions and false confessions, the Third Edition: Tackles new areas affected by globalization and new technologies, including human trafficking and internationally coordinated cybercrimes Expands discussion of border control, The Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF), and Homeland Security Addresses the effects of ever-evolving technology on the commission and detection of crime The definitive text in this field, Crime Classification Manual, Third Edition is written for law enforcement personnel, mental health professionals, forensic scientists, and those professionals whose work requires an understanding of criminal behavior and detection.
This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.
While tracking down a killer, clues lead homicide detective, Viviane Taylor to suspect, Julian DeMatteo. From the get-go, DeMatteo unsettles and irritates her. He's a force she has never encountered, someone who excites her even though he’s forbidden. Her instincts warn that he’s hiding something and she is determined to uncover those secrets. As king of the vampires, Julian DeMatteo protects the immortal clans. So, when the beautiful, bullheaded cop embroils herself within his world, he must choose between the woman who reminds him of the humanity he’s lost or his loyalty to his people. As confusing emotions awaken inside her, Viviane can either accept her fate as the one chosen to save the immortal race or lose her soul to darkness. With Julian’s help, she fights an evil that would rip her apart in order to forge a new future with the homicide suspect who’s stolen her heart.
This book provides an introduction to the complex field of ubiquitous computing Ubiquitous Computing (also commonly referred to as Pervasive Computing) describes the ways in which current technological models, based upon three base designs: smart (mobile, wireless, service) devices, smart environments (of embedded system devices) and smart interaction (between devices), relate to and support a computing vision for a greater range of computer devices, used in a greater range of (human, ICT and physical) environments and activities. The author details the rich potential of ubiquitous computing, the challenges involved in making it a reality, and the prerequisite technological infrastructure. Additionally, the book discusses the application and convergence of several current major and future computing trends. Key Features: Provides an introduction to the complex field of ubiquitous computing Describes how current technology models based upon six different technology form factors which have varying degrees of mobility wireless connectivity and service volatility: tabs, pads, boards, dust, skins and clay, enable the vision of ubiquitous computing Describes and explores how the three core designs (smart devices, environments and interaction) based upon current technology models can be applied to, and can evolve to, support a vision of ubiquitous computing and computing for the future Covers the principles of the following current technology models, including mobile wireless networks, service-oriented computing, human computer interaction, artificial intelligence, context-awareness, autonomous systems, micro-electromechanical systems, sensors, embedded controllers and robots Covers a range of interactions, between two or more UbiCom devices, between devices and people (HCI), between devices and the physical world. Includes an accompanying website with PowerPoint slides, problems and solutions, exercises, bibliography and further reading Graduate students in computer science, electrical engineering and telecommunications courses will find this a fascinating and useful introduction to the subject. It will also be of interest to ICT professionals, software and network developers and others interested in future trends and models of computing and interaction over the next decades.
Latest generation sequencing revolutionizes the fields of cancer research and oncology. This follow-up volume focuses more extensively on single cell sequencing of cancer and trials in drug resistance. Another exciting feature is the bioinformatics tools given, that can be used on cancer genome studies. Scientists around the world are attempting to find the root cause of cancer. A reasonable cancer treatment plan and potential cure is more optimistic now with the unfolding of the cancer genome. The collective knowledge of how to leverage next generation sequencing in cancer research is paving the way. The important information provided in this volume will move the field forward in developing novel targeted cancer therapies.
A Brief History of American Literature offers students and general readers a concise and up-to-date history of the full range of American writing from its origins until the present day. Represents the only up-to-date concise history of American literature Covers fiction, poetry, drama and non-fiction, as well as looking at other forms of literature including folktales, spirituals, the detective story, the thriller and science fiction Considers how our understanding of American literature has changed over the past twenty years Offers students an abridged version of History of American Literature, a book widely considered the standard survey text Provides an invaluable introduction to the subject for students of American literature, American studies and all those interested in the literature and culture of the United States
From smartphones to social media, from streaming videos to fitness bands, our devices bring us information and entertainment all day long, forming an intimate part of our lives. Their ubiquity represents a major shift in human experience, and although we often hold our devices dear, we do not always fully appreciate how their nearly constant presence can influence our lives for better and for worse. In this revised and expanded edition of How Fantasy Becomes Reality, social psychologist Karen E. Dill-Shackleford explains what the latest science tells us about how our devices influence our thoughts, feelings, and behaviors. In engaging, conversational prose, she discusses both the benefits and the risks that come with our current level of media saturation. The wide-ranging conversation explores Avatar, Mad Men, Grand Theft Auto, and Comic Con to address critical issues such as media violence, portrayals of social groups, political coverage, and fandom. Her conclusions will empower readers to make our favorite sources of entertainment and information work for us and not against us.
Murder, mayhem and magic… Locked in a coffin-like darkness, there is nothing to distract me from my memories of killing Reyad. He deserved to die—but according to the law, so do I. Here in Ixia, the punishment for murder is death. And now I wait for the hangman's noose. But the same law that condemns me may also save me. Ixia's food taster—chosen to ensure that the Commander's food is not poisoned—has died. And by law, the next prisoner who is scheduled to be executed—me—must be offered the position.
This book uniquely combines cutting-edge medical, psychological, and sociocultural topics pertinent to eating disorders. In the medical realm, the book focuses on Eating Disorders’ newly investigated associations with ADHD and sleep disorders, and on innovative treatments of osteoporosis in anorexia nervosa. Novel contributions in the psychological realm address families’ trans-generational transmission of Eating Disorders-related difficulties and novel internet-based treatments for such families. Lastly, in the sociocultural realm, the book discusses social contagion and Pro-Ana websites as increasing risk for disordered eating in young women around the globe. This volume provides readers with more holistic perspectives of each realm and their interplay, to promote Eating Disorders’ understanding, treatment, prevention, and research. It provides various professionals including mental health providers, physicians, nutritionists, and graduate students in these professions.
Twenty-three year old, Amari Hawke, is thrust into the world of two-soul shifters when she is injured and kidnapped by trackers outside the veil, beyond the safety of her homeland. Unable to remember her past, she trusts no one and relies on instinct to survive. As her awakening approaches, the first time she will transition into her animal, she must evade rogue shifters trying to capture her. Now free from the King’s Army, powerful dragon lord, Jaxon Blackthorn, seeks a peaceful life. Intent on building his lands into a viable plantation, away from war and bloodshed, he is reluctantly pulled back into the fight when he defends the mysterious shifter with no past against an unseen enemy. As evil threatens to destroy the entire realm, can the battle-hardened warrior and coming-of-age noblewoman accept their differences to forge an alliance that will ultimately unite the shifter nations?
Today, the moving image is ubiquitous in global contemporary art. The first book to tell the story of the postwar expanded cinema that inspired this omnipresence, Between the Black Box and the White Cube travels back to the 1950s and 1960s, when the rise of television caused movie theaters to lose their monopoly over the moving image, leading cinema to be installed directly alongside other forms of modern art. Explaining that the postwar expanded cinema was a response to both developments, Andrew V. Uroskie argues that, rather than a formal or technological innovation, the key change for artists involved a displacement of the moving image from the familiarity of the cinematic theater to original spaces and contexts. He shows how newly available, inexpensive film and video technology enabled artists such as Nam June Paik, Robert Whitman, Stan VanDerBeek, Robert Breer, and especially Andy Warhol to become filmmakers. Through their efforts to explore a fresh way of experiencing the moving image, these artists sought to reimagine the nature and possibilities of art in a post-cinematic age and helped to develop a novel space between the “black box” of the movie theater and the “white cube” of the art gallery. Packed with over one hundred illustrations, Between the Black Box and the White Cube is a compelling look at a seminal moment in the cultural life of the moving image and its emergence in contemporary art.
This text is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to technological advances the field trauma, critical care and many aspects of surgical science and practice. Care of these patients and clinical conditions can be quite complex, and materials have been collected from the most current, evidence-based resources. The sections of the text have been structured to review the overall scope of issues dealing with trauma, critical care and surgery, including cardiothoracic surgery, vascular surgery, urology, gynecology and obstetrics, fetal surgery and orthopedics. This volume represents the most comprehensive textbook covering a wide range of topics and technological advances including genomics and nanotechnologies that affect patients’ care and surgeons’ practice daily. The multidisciplinary authorship includes experts from all aspects of trauma, surgery and critical care. The volume highlights the dramatic changes in the field including hand held devices and smart phones used in daily medical and surgical practice, complex computers in the critical care units around the world, and robotics performing complex surgical procedures and tissue engineering. Technological Advances in Surgery, Trauma and Critical Care provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in trauma, critical care, and all the specialties of surgery. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
A History of Modern Drama: Volume II explores a remarkable breadth of topics and analytical approaches to the dramatic works, authors, and transitional events and movements that shaped world drama from 1960 through to the dawn of the new millennium. Features detailed analyses of plays and playwrights, examining the influence of a wide range of writers, from mainstream icons such as Harold Pinter and Edward Albee, to more unorthodox works by Peter Weiss and Sarah Kane Provides global coverage of both English and non-English dramas – including works from Africa and Asia to the Middle East Considers the influence of art, music, literature, architecture, society, politics, culture, and philosophy on the formation of postmodern dramatic literature Combines wide-ranging topics with original theories, international perspective, and philosophical and cultural context Completes a comprehensive two-part work examining modern world drama, and alongside A History of Modern Drama: Volume I, offers readers complete coverage of a full century in the evolution of global dramatic literature.
Part three and the exciting conclusion to the epic fantasy romance serial trilogy, Rogue Dragon Rising, marking the beginning of the Outside the Veil series. With no memories to guide her, Amari Hawke seeks to discover the identity of the animal trapped inside her. Days away from Trinity, when her beast will appear for the first time, she must learn to communicate with her animal or she’ll turn rogue from an unsuccessful shift. Both Jaxon Blackthorn and his stubborn dragon have succumbed to Amari’s charms even though her animal designation is unknown. Determined to use the power of his beast, Jaxon faces the impossible challenge of saving Amari while protecting her from rogue shifters determined to capture her. Can the strength of their love achieve what has never been attempted in the shifter realm, a successful transition of Amari’s animal and acceptance of her true heritage?
Part two in the exciting epic fantasy romance serial trilogy, Rogue Dragon Rising. As the day of her awakening nears, Amari Hawke struggles to control the beast inside her. Basking in the energy of the approaching Trinity moon, her animal’s strength has increased to the point it can control Amari’s mind and body. Fearing she is about to slip into madness, Amari is forced into a tough choice. In a desperate attempt to save Amari and her beast, Jaxon Blackthorn encourages his cadre, the men in his trusted circle, to establish mental links with her, but when his plans fail and Amari’s animal exerts control, he must fight for the beautiful woman who is lost to her beast. Together, can Amari and Jaxon’s developing bond for each other overcome the urges driving Amari’s animal as they also thwart an unseen enemy vying to keep them apart? Please note: Alpha Dragon Awakes, the third book in the serial trilogy and exciting conclusion to Jaxon and Amari’s story, is set to release in late December, 2018.
A Kirkus Reviews Best Book of 2016! An NPR Best Book of 2016! "I can say, without a doubt, that A Promise of Fire is going on my keeper shelf...I cannot remember the last time I wanted to both savor and devour a book." — Smart Bitches, Trashy Books KINGDOMS WILL RISE AND FALL FOR HER... BUT NOT IF SHE CAN HELP IT Catalia "Cat" Fisa lives disguised as a soothsayer in a traveling circus. She is perfectly content avoiding the danger and destiny the Gods-and her homicidal mother-have saddled her with. That is, until Griffin, an ambitious warlord from the magic-deprived south, fixes her with his steely gaze and upsets her illusion of safety forever. Griffin knows Cat is the Kingmaker, the woman who divines the truth through lies. He wants her as a powerful weapon for his newly conquered realm-until he realizes he wants her for much more than her magic. Cat fights him at every turn, but Griffin's fairness, loyalty, and smoldering advances make him increasingly hard to resist and leave her wondering if life really does have to be short, and lived alone. The Kingmaker Chronicles: A Promise of Fire (Book 1) Breath of Fire (Book 2, coming January 2017) Heart on Fire (Book 3, coming Fall 2017) Praise for The Kingmaker Chronicles "Breath of Fire is a heart-pounding and joyous romantic adventure that swept me away. Amanda Bouchet's talent is striking."—NALINI SINGH, New York Times bestselling author on Breath of Fire More Praise for A Promise of Fire: "I cannot remember the last time I wanted to both savor and devour a book." —Smart Bitches, Trashy Books "An exquisite high-fantasy romance with masterful worldbuilding." —Kirkus STARRED Review "Fantasy romance at its finest! You will fall in love with these delicious characters." —Darynda Jones, New York Times bestselling author of the Charley Davidson series "Bouchet skillfully melds the genres while crafting a sexy, emotional romance."—Sarah MacLean, The Washington Post "A Promise of Fire made me laugh out loud more than once."—Thea Harrison, New York Times bestselling author of the Elder Races series
In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses. Their work will broaden both the clinician's and the researcher's knowledge of basic mechanisms of immunological tolerance, viral immunosuppression, the nature of protective immune responses to vaccination, and viral effects on cell functions.
Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for Next-Generation Sequencing is an invaluable tool for students and researchers in bioinformatics and computational biology, biologists seeking to process and manage the data generated by next-generation sequencing, and as a textbook or a self-study resource. In addition to offering an in-depth description of the algorithms for processing sequencing data, it also presents useful case studies describing the applications of this technology.